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Secret Seeker

16,349 Comments

Legend of the Seeker
I haven’t said much about this show, but I have to admit that it is one of my favorites. This is my first time following a show that airs only in syndication, but I’m sure to catch every episode (DVR helps, of course). I haven’t read the book series the show is based on (The Sword of Truth), so I have the luxury of watching without criticizing, and maybe that’s part of my admiration. The cinematography is stunning and I like that the characters seem “real” in that they aren’t necessarily modelesque (though the 7th episode may challenge my notion on that front). If you find yourself with nothing to do this weekend, look the show up and give it a try.

I read this week that NBC is NOT going to show Merlin now, due to needing airtime to show more episodes of fat people trying to lose weight. Boo them. Not the fat people–NBC. For anyone wanting to see it, just let me know. :wink2:

In continuing my geekish fandom posts, I’m going to start posting my “Top 5” elements from various fandoms from now until the rest of year. I’d love to see if you share any of them! Check back soon! :elf:

16,349 thoughts on “Secret Seeker”

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  24. ### The Ultimate Guide to Services Cleaning: Why It Matters and How to Choose the Best

    In today’s fast-paced world, maintaining a clean and organized space is more important than ever. Whether it’s your home, office, or commercial property, *services cleaning* offers a practical solution to keep your environment spotless without the hassle. This article explores the benefits of professional cleaning services, what to look for when hiring a team, and why investing in these services is a smart choice for both individuals and businesses.

    #### What Are Services Cleaning?
    *Services cleaning* refers to professional cleaning solutions provided by trained experts who handle everything from routine tidying to deep sanitation. These services can be tailored to residential spaces, workplaces, or specialized facilities like gyms, restaurants, or medical offices. Unlike DIY cleaning, professional services bring expertise, advanced tools, and eco-friendly products to ensure a thorough and efficient job.

    #### The Benefits of Professional Services Cleaning
    Hiring a *services cleaning* provider comes with a range of advantages that go beyond just a shiny floor or dust-free shelves. Here’s why they’re worth considering:

    1. **Time-Saving Convenience**
    Life is busy, and cleaning often falls to the bottom of the priority list. Professional cleaning services free up your schedule, letting you focus on work, family, or relaxation while experts handle the dirt and grime.

    2. **Healthier Living Spaces**
    Dust, allergens, and bacteria can build up over time, affecting air quality and health. *Services cleaning* teams use specialized techniques and products to eliminate these hazards, creating a safer environment for you and your loved ones.

    3. **Enhanced Productivity for Businesses**
    A clean workspace isn’t just aesthetically pleasing—it boosts employee morale and efficiency. Regular *services cleaning* for offices ensures a professional atmosphere that leaves a lasting impression on clients and staff alike.

    4. **Customized Solutions**
    From carpet cleaning to window washing, professional services offer tailored packages to meet your specific needs. Whether it’s a one-time deep clean or ongoing maintenance, you get exactly what your space requires.

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    Not all cleaning services are created equal. To ensure you’re getting the best value for your money, here are some key factors to consider when selecting a *services cleaning* company:

    – **Reputation and Reviews**
    Look for providers with positive feedback from past clients. Online reviews and testimonials can give you insight into their reliability and quality of work.

    – **Experience and Expertise**
    A team with years of experience in *services cleaning* will know how to tackle tough stains, delicate surfaces, and industry-specific challenges (e.g., sanitizing a healthcare facility).

    – **Eco-Friendly Options**
    If sustainability matters to you, opt for a service that uses green cleaning products and practices. This not only benefits the planet but also reduces exposure to harsh chemicals.

    – **Flexible Scheduling**
    The best *services cleaning* companies work around your timetable, offering evening, weekend, or emergency cleaning options to minimize disruption.

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    #### When Should You Invest in Services Cleaning?
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    – **Post-Renovation**: Construction dust and debris require heavy-duty cleaning that’s best left to the pros.
    – **Seasonal Refresh**: Spring cleaning or pre-holiday tidying can benefit from expert help.
    – **Business Upkeep**: Regular cleaning keeps commercial spaces presentable and hygienic year-round.

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  28. Degree of proof for creatine supplementation for persistent, atraumatic mitochondrial dysfunction. Stage of evidence for creatine supplementation in acute traumatic mitochondrial dysfunction. Eighteen male volunteers were initially enrolled within the examine; however, 4 have been excluded, thus, fourteen men [mean ± SD; age 24 ± four years; top 173.8 ± 6.2 cm; whole physique mass 73.4 ± 7.4 kg] accomplished participation in the examine.
    Training volume was calculated by multiplying the amount of weight lifted occasions the number of repetitions performed for every set performed. Complete training volume during the examine was analyzed by summing all lifts (upper and lower body) to determine if there have been any differences amongst groups. In the kidneys, the enzyme AGAT catalyzes the conversion of two amino acids — arginine and glycine — into guanidinoacetate (also referred to as glycocyamine or GAA), which is then transported in the blood to the liver. A methyl group is added to GAA from the amino acid methionine by the enzyme GAMT, forming non-phosphorylated creatine. This is then released into the blood by the liver where it travels mainly to the muscle cells (95% of the physique’s creatine is in muscles), and to a lesser extent the mind, coronary heart, and pancreas. Once contained in the cells it’s remodeled into phosphocreatine by the enzyme advanced creatine kinase.
    With a focus on practical health and strength training, Justin goals to inspire and motivate others to realize their health objectives. When he is not understanding or writing, he could be discovered exploring the good outside or spending time together with his household. In this comprehensive guide, we’ll evaluate creatine monohydrate and creatine ethyl ester side-by-side to assist you determine which type is best for you.
    This disparity may be attributed to the higher proportion of kind II muscle fibers in males, an element known to affect responsiveness to creatine supplementation [52]. Muscle fiber kind distribution has been proven to play a job in responding to creatine supplementation [52]. In the absence of muscle biopsies, relative 15-s work may perform as an indicator for a higher fraction of type II fibers. Nonetheless, no such significant relation between elevated 15-s work underneath the creatine condition and relative 15-s work was present in our information. This study aimed to evaluate the influence of creatine monohydrate supplementation on a 15-s all-out sprint take a look at efficiency, FFM, and ?La.
    Volunteers who have been often absent from the trials or offered injuries had been excluded from the examine. Some research (Bertuzzi et al., 2010; Zagatto et al., 2016; Miyagi et al., 2017) have proposed another technique to estimate the AC, denominated alternative MAOD. Nevertheless, the alternative MAOD doesn’t measure oxygen deficit, thus we’ll name it AC estimated by the non-oxidative energetics sum measured throughout a single supramaximal effort (AC[La-]+EPOCfast). Collectively, these findings suggest that AC[La-]+EPOCfast could presumably be more delicate to detect small adjustments when in comparability with standard MAOD.
    Individuals with this response could additionally be limited of their power output not by glycolytic vitality contribution but quite by neuromuscular or mechanical factors such as the testing setup [2,22]. A change in ?La is noteworthy because 1) it’s the main parameter for calculating ?Lamax, and 2) we identified differences between conditions in glycolytic contribution calculations as primarily related to variations in ?La. Individual results with differences between conditions are displayed in Figure three.
    Creatine is of course occurring in our our bodies and is found in the muscle cells as a way to give us power as we grind through those huge lifts. In quick, after you eat protein, your kidneys and liver work to make your body’s personal creatine provide. This then makes it’s way to your muscular tissues where it’s transformed to creatine phosphate and in the end adenosine triphosphate, which is now available and prepared to be used for power. With comparable properties to amino acids, creatine has great skills in serving to with muscle progress and recovery, in addition to a bunch of different bodily capabilities.
    Powdered creatine supplements—available in flavored and non-flavored varieties—need to be added to a beverage (like water or a protein shake) however allow you to divvy up dosages all through the day simply. This is handy each for those in a loading section in addition to those sticking with a regular dosage. Capsule supplements may appear extra handy, however loading with them might involve downing handfuls of capsules throughout the day. Bloating and GI discomfort are potential unwanted facet effects of creatine supplementation, and analysis exhibits that tummy troubles following ingestion usually tend to accompany larger doses (10 grams or more).
    There was, nevertheless, little distinction between the 2 teams in phrases of lean muscle mass and muscle energy. Kre-Alkalyn tackles these results by adjusting the pH of monohydrate creatine with alkaline powder, similar to magnesium, soda ash, or bicarbonate. In this strategy, Kre-Alkalyn can supply concentrated creatine levels without changing it to creatinine, which has many opposed effects. Researchers have discovered that taking creatine every day for simply four to 10 days can improve brain operate by as much as 15 percent during checks that measure response time, short-term memory, and impulse control. By adding an alkaline powder such as (soda ash, magnesium glycerol phosphate, bicarbonate) to strange creatine monohydrate, it stabilizes the acidity level between 7-14, making it more bioavailable and inhibiting the process of creatinine conversion. Additional evaluations involving human scientific trials are needed to find out solubility of Creatine HCL compared to creatine monohydrate. A rat study found that Creatine HCl was 38 instances extra soluble than creatine monohydrate [R].
    The product is claimed to be the one solubilized type of powdered creatine in the market, making it more bioavailable and secure. Nevertheless, no evidence has been published thus far to substantiate any efficiency or ergogenic benefit from this type of creatine. Tallon et al. (Child and Tallon 2007) compared the stability of creatine ethyl ester (CEE) head to head with CM and found that CEE was actually much less stable than CM. It was concluded that the addition of the ethyl group to creatine really lowered acid stability and accelerated its breakdown to creatinine. It is speculated that the methyl ester or ethyl ester teams are better leaving groups than hydroxyl or water and, subsequently, suggesting that the degradation into creatinine ought to be somewhat accelerated.
    To date, Spillane et al. (2009) are the only group that has studied the impression of CEE supplementation on training variations in resistance educated individuals. The researchers randomly assigned in a double-blind manner 30 male resistance-trained athletes to ingest zero.30 g/kg per day fat-free mass (about 20 g/day) of both a placebo, CM, or CEE for 42 days. As stated beforehand, CEE supplementation did not promote larger whole muscle creatine levels in comparability to placebo. In terms of coaching diversifications, CEE supplementation did not promote greater gains in body mass, fat-free mass, power, or dash performance. These findings indicate that CEE has no obvious ergogenic value over CM despite widespread claims that it is a extra superior form of creatine. Moreover, the considerably larger creatinine ranges observed point out it’s degraded to a larger degree and will pose higher security considerations.
    On the other hand, Creatine hydrochloride is created by attaching creatine to a hydrochloride group. This type of creatine has much greater aqueous solubility, that means that it mixes higher with liquid, making it simpler for the body to soak up and retain than creatine monohydrate. When ingested, creatine binds itself to a phosphate molecule and types creatine phosphate.
    Moreover, although lactate concentration is commonly used to determine resistance training intensity, this variable was not evaluated to find out functional capability, which can be considered a further limitation on this research. Consultant photos of hematoxylin-eosin-stained muscle transverse sections are proven in Determine 2. The cross-sectional space of fibers from the gastrocnemius white portion was increased in response to resistance train coaching (Cc 3731 ± 415; Cr 3977 ± 422; Tr 4813 ± 982; Tcr 4273 ± 305 µm2, Figure 2A). On the other hand, soleus cross-sectional areas didn’t differ between the groups (Cc 3997 ± 353; Cr 3910 ± 289; Tr 3642 ± 360; Tcr 4247 ± 736 µm2, Determine 2B).
    Bemben et al [24] have shown no further benefits of creatine alone or mixed with whey protein for bettering energy and muscle mass after a progressive 14 weeks (3 days per week) resistance training program in older males. These conflicting results can be explained by the likelihood that the supplemented teams have been shaped by a greater quantity of non-responders or even as a end result of creatine supplementation was administered on the training days solely (3 occasions a week). This strategy has not been adequately examined as effective in middle aged and older males for sustaining publish loading elevated creatine shops [5]. Creatine (N-aminoiminomethyl-N-methyl glycine) is a naturally occurring and nitrogen-containing compound comprised from amino acids that’s categorized within the family of guanidine phosphagens [1,33]. Creatine is synthesized endogenously from arginine and glycine by arginine glycine amidinotransferase (AGAT) to guanidinoacetate (GAA).
    Phosphagenic sources contribute greater than half of the vitality in a 15-s all-out sprint [7]. Twenty male and 5 female cyclists underwent a placebo-controlled, crossover design with 4 laboratory visits. Placebo (4 × 5 g/d maltodextrin) and creatine monohydrate (4 × 5 g/d) had been administered for five d earlier than the respective trials. All individuals underwent this order of trials and carried out a 15-s all-out sprint check on a Cyclus2-ergometer.
    Over many years, research has repeatedly confirmed its helpful effect on the multiplicity of features of the functioning of the human body. Many scientific research have also confirmed adrenalines participation all through the method, as it promotes the initiation of protein synthesis. The next step in this complicated sequence is the protein binding to GTP (guanidinotriphosphate), a compound that’s a results of delivery of ATP by creatine. These, in flip, are activated by nitrogen oxide and revert to ATP and GTP leading to cyclic nucleotides -cAMP or cGMP. However, the restricted analysis obtainable means that we can’t make such claims with absolute certainty. Creatine monohydrate has been researched extensively and is a confirmed supplement with many demonstrable advantages for athletes and fitness enthusiasts.
    It is healthier soluble in water, easier to assimilate, and the increments it generates seem to be more steady. It is structured as a nucleoside triphosphate consisting of a nitrogenous base (adenine), ribose sugar, and phosphate groups, which are serially bonded. As the “energy currency” for cells, ATP supplies the power for 2 of the three phosphate teams (1). Creatine might work together with different neurotransmitter methods, such as the monoamines and adenosine.
    This has made creatine essentially the most coveted nutritional supplement amongst fitness lovers and athletes. Seaweeds such as Spirulina comprise probably the most quantity of creatine which is about 0.86g. It also helps to decrease the physique weight by not allowing the physique to absorb fat (25). The high content of creatine in pork makes it great for bodybuilders, recovering athletes, people post-surgery, or others who must construct up or restore muscle tissue (8).
    The authors instructed that there are different methods, in addition to a quantity of components, that enable creatine uptake in the muscle when compared to the brain. Creatine synthesis was also ruled out since synthesis has not been observed in skeletal muscle in people nor in animal models. This research clarifies that muscle and mind respond differently to creatine transport. Potential side effects of creatine supplementation embody diarrhea, muscle cramps, and elevated blood strain. Meta-analyses and reviews have concluded that monohydrate supplementation improves athletic performance (particularly for more intense actions, corresponding to sprinting and weight training), helps muscle restoration, and should enhance overall cognition. Creatine helps adenosine triphosphate (ATP) synthesis (energy production), which is especially beneficial during intense train. Throughout this train, the body can break down ATP molecules (the body’s energy currency) up to one thousand instances faster than usual.
    During supplementation and the washout period, the volunteers maintained their recreational exercise routine. A very low pH ends in the protonation of the amide function of the creatine molecule, thereby stopping the intramolecular cyclization (see Fig. 6). This effect additionally occurs beneath the acidic conditions in the abdomen, therefore preventing the breakdown of creatine. The conversion of creatine to creatinine within the gastrointestinal tract is minimal regardless of transit time (Persky et al. 2003; Harris et al. 1992b; Deldicque et al. 2008). Creatine monohydrate accommodates 87.9% of creatine, whereas the creatine content material in other forms of creatine is decrease with the exception of creatine anhydrous (see Table 1). Commercial creatine salts are fashioned in solution or by mechanical processes such as milling or grinding under the presence of residual water. Complexes are formed by the subsequent replacement of the solvating molecules by the brand new ligands.

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